Extracellular vesicle-mediated immune regulation in central nervous system diseases: Mechanistic insights and exercise interventions.

A review published in Brain Research Bulletin examines how extracellular vesicles (EVs) modulate immune responses in central nervous system disorders, with a focus on the role physical exercise plays in influencing EV-mediated signaling. The authors explore mechanistic pathways through which exercise-induced EVs may help regulate neuroinflammation across conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. These findings have potential implications for exercise-based rehabilitation strategies used in neurological physical therapy.

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